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Signaling Antibodies

Featured Signaling Products
Anti-Ubiquitin K11 linkage, clone 2A3/2E6Anti-Ubiquitin K11 linkage, clone 2A3/2E6
K11-linked ubiquitin chains seem to have essential regulatory control over mitotic protein degradation. The lysine11 (K11) linkage of ubiquitin has been shown to be specifically targeted by the Anaphase-Promoting Complex (APC) E3 ubiquitin ligase for catalyzed ubiquitination for mitosis.

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Anti-Axin-2Anti-Axin-2
Axis inhibition protein 2 (Axin-2) has been linked to selective tooth angenesis. It has been found in human thymus, prostate, testis, small intestine, ovarian tissue and in the colon, at a lower expression rate. Axin-2 is involved during skull morphogenesis and missing Axin-2 can cause abnormal skull morphology. Variation in Axin-2 has been associated with accelerated chondrocyte proliferation.

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