 Brain and muscle Arnt-like protein-1 (BMAL1) is a transcription factor known to regulate circadian rhythm. BMAL1 is acetylated at Lys538 upon heterodimerization with CLOCK to effect regulation of glucose homeostasis and metabolism. This BMAL1 antibody recognizes BMAL1 from multiple species in Western blots. |  The transcription factor CCAAT/Enhancer Binding Protein beta (C/EBPβ, also known as NFIL6) is a highly conserved B-Zip family member. C/EBPβ regulates multiple genes involved in hepatic function, immune function and adipogenesis, and acetylation at Lysines 215 and 216 may determine its specificity of action. |
 Immunoprecipitate transcriptionally active chromatin from mammalian cells using anti-acetyl-Histone H3. Detection of the gene or promoter of interest in immunoprecipitated chromatin must be empirically determined using quantitative PCR or Southern blot analysis with promoter-specific primers or probe. |  This 384 well format kit is a newer version of the tried and true non-radiographic HDAC assay. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Routinely evaluated by deacetylation of HDAC Assay Substrate using HeLa nuclear extract. |