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Featured Stem Cell Research Products EMD Millipore’s Human STEMCCA Cre-Excisable Constitutive Polycistronic (OKS/L-Myc) Lentivirus Kit contains high titer Cre-excisable polycistronic (OKS/L-Myc) lentivirus, three small molecule rerogramming supplements, and Polybrene® transfection reagent. The use of L-Myc in the context of an excisable single lentiviral vector instead of four separate vectors for the derivation of iPS cells significantly reduces the risks of transformation, insertional mutagenesis and viral reactivation and is a step towards safer utilization of iPS technology for disease models and clinical therapies.  EMD Millipore’s Human iPS Cell Boost Supplement II contains three proprietary small molecules (TGF-β RI Kinase Inhibitor IV, Sodium Butyrate and PS48) in amounts sufficient to supplement 350 mL of human ES cell maintenance medium. When used in conjunction with the Human STEMCCA lentivirus reprogramming kits (SCR544, SCR545, and SCR548), the Human iPS Cell Boost Supplement II enhances the efficiency of human iPS colony formation by 10 – 15 fold and shortens the timescale to establish fully reprogrammed colonies by 50%. Animal Free Human Recombinant Growth Factors Commonly used human recombinant growth factors manufactured in a completely animal free enviroment to maintain Xeno-Free culture conditions. |
