Immunoassays and Multiplex Solutions for Cell Signaling Research - MILLIPLEX MAP

MILLIPLEX MAP Kits and Panels for Cell Signaling Research

Reach faster, improved research decisions using multiplexed biomarker detection. Because many signaling pathways are interconnected, multiparametric sample analysis is essential for successful cell signaling research. Using Luminex xMAP technology, MILLIPLEX MAP panels are validated and optimized to yield maximum data from your precious samples.

Analytes featured in Millipore’s MILLIPLEX MAP Cell Signaling Kits have been analytically validated together. Each kit includes all the reagents necessary to run an assay on 35 25-μL samples in duplicate—all in one kit, with one catalogue number.

New multiplex panels, including cell signaling proteins and new signaling pathways, will be introduced into our portfolio each quarter—sign up here to download a pdf or receive a hard copy of this quarter's update.

Human STAT - 5 Plex Catalogue Number: 48-610 (nonmagnetic) Catalogue Number: 48-610MAG (magnetic) STAT1 (Tyr701) STAT2 (Tyr690) STAT3 (Tyr705) STAT5A/B (Tyr694/699) STAT6 (Tyr641)	Human Multi-Pathway 9 Plex Catalogue Number: 48-680MAG (magnetic) Akt (Ser473) CREB (Ser133) Erk/MAPK 1/2 (Thr185/Tyr187) NFκB (Ser536) JNK/SAPK1 (Thr183/Tyr185) p38/SAPK2A/B (Thr180/Tyr182) p70 S6 Kinase (Thr412) STAT3 (Ser727) STAT5A/B (Tyr694/699)

Human T Cell Receptor – 7 Plex Catalogue Number: 48-690 (magnetic) CD3ε (pan Tyr) CREB (Ser133) Erk/MAPK 1/2 (Thr185/Tyr187) LAT (pan Tyr) Lck (pan Tyr) Syk (pan Tyr) ZAP-70 (pan Tyr)	Human MAP/SAPK 10 Plex Catalogue Number: 48-660 (magnetic) ATF2 (Thr69/71) c-Jun (Ser73) Erk/MAPK 1/2 (Thr185/Tyr187) HSP27 (Ser78) JNK/SAPK1 (Thr183/Tyr185) MEK1 (Ser222) MSK1 (Ser212) p38/SAPK2A/B (Thr180/Tyr182) p53 (Ser15) STAT1 (Tyr701)

Src Family Kinase Active Site 8 Plex Catalogue Number: 48-650MAG (magnetic) Blk (Tyr389) Fgr (Tyr412) Fyn (Tyr420) Hck (Tyr411) Lck (Tyr394) Src (Tyr419) Yes (Tyr421)	Human Late Apoptosis 3 Plex Catalogue Number: 48-670MAG (magnetic) Caspase 3 (Active) GAPDH (Total) PARP (Cleaved)

	MILLIPLEX MAP Akt/mTOR Phosphoprotein Magnetic Bead 11-Plex Kit Catalogue Number: 48-611MAG (magnetic) Akt (Ser473) GSK3α (Ser21) GSK3β (Ser9) IGF1R (Tyr1135/Tyr1136) IR (Tyr1162/Tyr1163) IRS1 (Ser312) PTEN (Ser380) RPS6 (Ser235/Ser236) TSC2 (Ser939) mTOR (Ser2448) p70S6K (Thr412)

MILLIPLEX MAP Total Akt/mTOR Magnetic Bead 11-Plex Kit Catalogue Number: 48-612MAG (magnetic) Akt (Total) GSK3α (Total) GSK3β (Total) IGF-1R (Total) IR (Total) IRS1 (Total) PTEN (Total) RPS6 (Total) TSC2 (Total) mTOR (Total) p70S6K (Total)	MILLIPLEX MAP EGFR Profiler Magnetic Bead 8-Plex Kit Catalogue Number: 48-613MAG (magnetic) EGFR (Ser1047) EGFR (Thr654) EGFR (Thr669) EGFR (Tyr1045) EGFR (Tyr1068) EGFR (Tyr1086) EGFR (Tyr845) EGFR (Total)

MILLIPLEX MAP Heat Shock Protein Magnetic Bead Panel Catalogue Number: 48-615MAG (magnetic) HSP27 (Total) HSP27 (pS78/pS82) HSP60 HSP70 HSP90α	MILLIPLEX MAP Human Phospho Mitogenesis RTK Magnetic Bead 7-Plex Kit Catalogue Number: 48-672MAG (magnetic) c-Met/HGFR (panTyr) EGFR (pan Tyr) ErbB2/HER2 (pan Tyr) ErbB3/HER3 (panTyr) ErbB4/HER4 (panTyr) IGF-1R (pan Tyr) IR (panTyr)

MILLIPLEX MAP Human Total Mitogenesis RTK Magnetic Bead 7-Plex Kit Catalogue Number: 48-671MAG (magnetic) c-Met/HGFR (total) EGFR (total) ErbB2/HER2 (total) ErbB3/HER3 (total) ErbB4/HER4 (total) IGF-1R (total) IR (total)	MILLIPLEX MAP Human TGFβ Singaling Pathway Magnetic Bead 6-Plex Kit Catalogue Number: 48-614MAG (magnetic) Akt (Ser473) ERK (Thr185/Tyr187) Smad2 (Ser465/Ser467) Smad3 (Ser423/Ser425) Smad4 (total) TGFβRII (total)

Src Family Kinase Active Site — 8 Plex Catalogue Number: 48-650MAG (magnetic) Blk (Tyr389) Fgr (Tyr412) Fyn (Tyr420) Hck (Tyr411) Lck (Tyr394) Src (Tyr419) Yes (Tyr421)	Human Angiogenesis RTK — 10 Plex Catalogue Number: 48-674MAG (magnetic) c-Kit 3 (pan Tyr) Flt3 3 (pan Tyr) M-CSFR 3 (pan Tyr) PDGFRα 3 (pan Tyr) PDGFRβ 3 (pan Tyr) Tie1 3 (pan Tyr) Tie2 3 (pan Tyr) VEGF R1 3 (pan Tyr) VEGF R2 3 (pan Tyr) VEGF R3 3 (pan Tyr)

Human Total Angiogenesis RTK — 10 Plex Catalogue Number: 48-673MAG (magnetic) c-Kit Flt3 M-CSFR PDGFRα PDGFRβ Tie1 Tie2 VEGF R1 VEGF R2 VEGF R3	Early Apoptosis — 7 Plex Catalogue Number: 48-669MAG (magnetic) Analyte Total Phosphorylated Akt 3 (Ser473) BAD 3 (Ser112) Bcl-2 3 (Ser70) Active Caspase 8 3 Active Caspase 9 3 JNK 3 (Thr183/Tyr185) p53 3 (Ser46)

Akt — 2 Plex Catalogue Number: 48-618MAG (magnetic) Analyte Total Phosphorylated Akt 3 Akt 3 (Ser473)	Erk / MAPK 1/2 — 2 Plex Catalogue Number: 48-619MAG (magnetic) Analyte Total Phosphorylated Erk 3 Erk 3 (Thr185/Tyr187)