Isotyping Assays

Produced by plasma cells and lymphocytes, immunoglobulins (Igs) are critically involved in immune response, attaching to antigens and playing a role in their destruction. Igs can be classified by isotype, classes that differ in function and antigen response due to structure variability. Five major isotypes are: IgM, IgG, IgA, IgE and IgD – all found in normal individuals. Some autoimmune diseases, GI conditions and malignancies are characterized by specific isotype deficiencies or varying concentrations of one or more isotypes. Disease states can range from the absence of one isotype class or subclass to a total deficiency of Ig classes.

Quantitate Ig classes and subclasses simultaneously with our MILLIPLEX MAP Isotyping Kits. The xMAP multiplex technology is ideal for measuring levels of these isotypes, not only decreasing the number of assays as well as the amount of sample required, but also greatly reducing the possible inaccuracies that result from performing multiple assays.

New MILLIPLEX MAP multiplex panels and ELISAs, including cytokine and chemokine biomarkers, will be introduced into our portfolio each quarter—sign up here to download a pdf or receive a hard copy of this quarter's update.

MILLIPLEX MAP Mouse Immunoglobulin Isotyping Magnetic Bead Panel
Catalogue Number: MGAMMAG-300K (magnetic)
  • IgA
  • IgG1
  • IgG2a
  • IgG2b
  • IgG3
  • IgM
MILLIPLEX MAP Human Isotyping Panel
Catalogue Number: HGAMMAG-301K (magnetic)
  • IgA
  • IgG1
  • IgG2
  • IgG3
  • IgG4
  • IgM
MILLIPLEX MAP Mouse IgE Single Plex Kit
Catalogue Number: MGAM-302E (nonmagnetic)
  • IgE
MILLIPLEX MAP Human IgE Single Plex Kit
Catalogue Number: HGAMMAG-303E (magnetic)
  • IgE