Ordering Information
- : 05-164
- : 100 µg
Anti-PLCβ-1 Antibody | 05-164
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| B, H, M, R | IP | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-PLCβ-1 Antibody | 05-164
Promotional Text:
Trade Name:
Upstate (Millipore)
Specificity:
PLCβ-1, also recognize the 100kDa and 41kDa fragments of PLCβ-1.1
Molecular Weight:
150 kDa
Immunogen:
Mixed monoclonal antibodies raised against purified bovine PLCβ-1
Isotype:
mixed IgGs
Species Reactivity:
- Bovine
- Human
- Mouse
- Rat
Quality Assurance:
routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody
Purification Method:
Protein G chromatography
Presentation:
100mM Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Storage Conditions:
2 years at -20°C
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- PLCB1
- PLC-beta-1
- PLC-154
- PLC-I
- KIAA0581
- FLJ45792
- 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
- PI-PLC
- inositoltrisphosphohydrolase
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Immunoprecipitation
Entrez Gene Summary:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Summary:
FUNCTION: SwissProt: Q9NQ66 # The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
COFACTOR: Calcium.
SIZE: 1216 amino acids; 138567 Da
SIMILARITY: SwissProt: Q9NQ66 ## Contains 1 C2 domain. & Contains 1 PI-PLC X-box domain. & Contains 1 PI-PLC Y-box domain.
MISCELLANEOUS: The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11.
COFACTOR: Calcium.
SIZE: 1216 amino acids; 138567 Da
SIMILARITY: SwissProt: Q9NQ66 ## Contains 1 C2 domain. & Contains 1 PI-PLC X-box domain. & Contains 1 PI-PLC Y-box domain.
MISCELLANEOUS: The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11.
Brand Family:
Upstate
Product Name:
Anti-PLCβ-1 Antibody | 05-164
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 µg
Format:
Purified
Host:
Mouse