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Ordering Information
- : 06-568
- : 200 µg
Product Images
IP: PI 3-Kinase p110 was IP'd with Anti-PI3 Kinase p110 beta, co-precipitation of p85 was detected with 06-195
Anti-PI3 Kinase, p110β
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| B, H, M, R | IP | Rabbit | Purified | Polyclonal Antibody |
Description:
Anti-PI3 Kinase, p110β
Trade Name:
Upstate (Millipore)
Specificity:
beta catalytic subunit and co-immunoprecipitates the regulatory subunit
Molecular Weight:
110kDa (beta catalytic subunit) and 85kDa (regulatory subunit)
Immunogen:
peptide (CKTINPSKYQTIRKAGKVH) corresponding to residues 418-435 of the human 110kDα PI 3-kinase
Isotype:
IgG
Species Reactivity:
- Bovine
- Human
- Mouse
- Rat
Application Notes:
Immunoblot is NOT recommended.
Quality Assurance:
routinely evaluated by immunoprecipitating the 110kDa catalytic subunit and the p85kDa regulatory subunit of PI 3-kinase beta. Subsequent immunoblotting was performed using anti-Rat PI 3-kinase (Catalog #06-195)
Purification Method:
Protein A chromatography
Presentation:
0.1M Tris-glycine, pH 7.0
Storage Conditions:
2 years at -20°C
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- PIK3CB
- DKFZp779K1237
- MGC133043
- PI3K
- p110-BETA
- PI3Kbeta
- PIK3C1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993 [PubMed 8246984]).[supplied by OMIM]
Key Applications:
Immunoprecipitation
UniProt Summary:
FUNCTION: SwissProt: P42338 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
SIZE: 1070 amino acids; 122762 Da
SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit.
TISSUE SPECIFICITY: Expressed ubiquitously.
SIMILARITY: SwissProt: P42338 ## Belongs to the PI3/PI4-kinase family. & Contains 1 PI3K/PI4K domain.
SIZE: 1070 amino acids; 122762 Da
SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit.
TISSUE SPECIFICITY: Expressed ubiquitously.
SIMILARITY: SwissProt: P42338 ## Belongs to the PI3/PI4-kinase family. & Contains 1 PI3K/PI4K domain.
Qty/Pk:
200 µg
Brand Family:
Upstate
Format:
Purified
Host:
Rabbit
Product Name:
Anti-PI3 Kinase, p110β
Antibody Type:
Polyclonal Antibody