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WB: Cell membranes from Hi5 insect cells expressing recombinant Flt-1 probed with anti-Flt-1 at 1µg/ml
Anti-Flt-1, CT
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | WB | Chicken | Purified | Polyclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: P17948 # Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
SIZE: 1338 amino acids; 150769 Da
SUBUNIT: Interacts in vitro with various phosphotyrosine-binding proteins, including PLC-gammas, PTPN11, GRB2, CRK and NCK1.
SUBCELL ... see more »
SIZE: 1338 amino acids; 150769 Da
SUBUNIT: Interacts in vitro with various phosphotyrosine-binding proteins, including PLC-gammas, PTPN11, GRB2, CRK and NCK1.
SUBCELL ... see more »
Entrez Gene Number:
Entrez Gene Summary
Oncogene FLT belongs to the src gene family and is related to oncogene ROS (MIM 165020). Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene (MIM 164770); hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase.[supplied by OMIM]
Description:
Anti-Flt-1, CT
Specificity:
Flt-1
Key Applications:
Western Blotting
Species Reactivity:
Human
Isotype:
IgY
Immunogen:
22 residue synthetic peptide (DDVRYVNAFKFMSLERIKTFEE) corresponding to amino acids 1209-1230 of human Flt-1
Molecular Weight:
180 kDa
Presentation:
sterile PBS, 0.05% sodium azide
Storage Conditions:
2 years at -20°C
Gene Symbol:
- FLT1
- VEGFR1
- FLT
- FRT
- VEGFR-1
- Flt-1
Quality Assurance:
routinely evaluated by immunoblot on a membrane preparation from Hi5 insect cells expressing recombinant Flt-1
Antibody Category:
Inflammation & Immunology
Antibody Sub-Category:
Cytokines & Cytokine Receptors
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Purification Method:
PEG and Ammonium Sulfate precipitation
Format:
Purified
Antibody Type:
Polyclonal Antibody
Host:
Chicken