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Ordering Information

  • : 07-205
  • : 100 µL

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WB: A431 cell lysate was probed with Anti-Sec61 β

Anti-Sec61β Antibody

Species Reactivity Key Applications Host Format Antibody Type
Ca, H IP, WB Rabbit Serum Polyclonal Antibody
Description:
Anti-Sec61β Antibody
Promotional Text:
Trade Name:
Upstate (Millipore)
Specificity:
Sec61β
Molecular Weight:
14kDa
Immunogen:
peptide conjugated to KLH corresponding to amino acids 2-10 of human Sec61β (PGPTPSGTN-C)
Isotype:
Species Reactivity:
  • Canine
  • Human
Quality Assurance:
routinely evaluated by immunoblot on RIPA lysates from non-stimulated A431 cells
Purification Method:
Antiserum
Presentation:
antiserum containing 0.05% sodium azide and 30% glycerol
Storage Conditions:
2 years at -20°C
UniProt Number:
Entrez Gene Number:
Gene Symbol:
SEC61B
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
  • Immunoprecipitation
  • Western Blotting
Entrez Gene Summary:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
UniProt Summary:
FUNCTION: SwissProt: P60468 # Necessary for protein translocation in the endoplasmic reticulum.
SIZE: 96 amino acids; 9974 Da
SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61- beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62.
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein.
SIMILARITY: SwissProt: P60468 ## Belongs to the SEC61-beta family.
Brand Family:
Upstate
Product Name:
Anti-Sec61β Antibody
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 µL
Format:
Serum
Host:
Rabbit
Applications:
Anti-Sec61β Antibody detects level of Sec61β & has been published & validated for use in IP & WB.

Product Resources

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