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WB: 20 micrograms of 3T3/A31 cell lysate was probed with 0.5μg/ml Anti-phospho-beta 2-Adrenergic Receptor (Thr384).
Anti-phospho-β-2 Adrenergic Receptor (Thr384)
| 交差性 | 主要アプリケーション | 免疫動物 | フォーマット | 抗体タイプ |
|---|---|---|---|---|
| H, M, R | WB | Rabbit | Purified | Polyclonal Antibody |
Description:
Anti-phospho-β-2 Adrenergic Receptor (Thr384)
Trade Name:
Upstate (Millipore)
Specificity:
phospho-beta 2-Adrenergic Receptor (Thr384)
Molecular Weight:
43kDa
Immunogen:
synthetic peptide containing the sequence PGpTED in which pT corresponds to phosphothreonine at residue 384 of human beta 2-Adrenergic Receptor
Modifications:
Phosphorylation
Isotype:
IgG
Species Reactivity:
- Human
- Mouse
- Rat
Quality Assurance:
routinely evaluated by immunoblot in RIPA lysates from 3T3/A31 cells.
Purification Method:
Protein A purfied
Presentation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%.
Storage Conditions:
2 years at -20°C
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- ADRBK2
- GRK3
- Beta-ARK-2
- BARK2
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: SwissProt: P35626 # Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
SIZE: 688 amino acids; 79710 Da
SIMILARITY: SwissProt: P35626 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 PH domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
SIZE: 688 amino acids; 79710 Da
SIMILARITY: SwissProt: P35626 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 PH domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
Qty/Pk:
200 µg
Brand Family:
Upstate
Format:
Purified
Host:
Rabbit
Product Name:
Anti-phospho-β-2 Adrenergic Receptor (Thr384)
Antibody Type:
Polyclonal Antibody