Información pedidos
Imágenes del producto
IHC: Staining of a 50µm Vibratome section of the hippocampus of an Alzheimer's patient incubated with anti-GFAP+1. (Cat. # 07-650; 1:1,000 ...
WB: Recombinant C-terminal GFAP+1 (~119 amino acids) was resolved by electrophoresis, transferred to nitrocellulose and probed with anti- ...
Anti-GFAP+1
| Reactividad de especies | Aplicaciones claves | Huésped | Formato | Tipo de anticuerpo |
|---|---|---|---|---|
| H | WB, IH | Rabbit | Serum | Polyclonal Antibody |
Número UniProt:
UniProt Summary
FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander diseas ... ver más »
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander diseas ... ver más »
Número GenBank:
Entrez Gene Summary
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined.
Description:
Anti-GFAP+1
Specificity:
GFAP+1
Key Applications:
- Western Blotting
- Immunohistochemistry
Species Reactivity:
Human
Isotype:
IgG
Immunogen:
synthetic peptide corresponding to a neo-C-terminus generated as a result of alternative splicing of the human GFAP mRNA (Hol et al, 2003)
Molecular Weight:
50kDa
Presentation:
antiserum containing 0.05% sodium azide and 30% glycerol.
Storage Conditions:
1 year at -20°C
Gene Symbol:
- GFAP
- FLJ45472
Quality Assurance:
Routinely evaluated by immunoblot of GFAP+1 protein
Antibody Category:
Neuroscience
Antibody Sub-Category:
Neurodegenerative Diseases
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Upstate (Millipore)
Format:
Serum
Host:
Rabbit
Antibody Type:
Polyclonal Antibody
Purification Method:
serum