Ordering Information
- : 07-742
- : 100 μg
- : 0.5 mg/mL
Product Images
Western Blot (Snap ID) Analysis:
Representative lot data.
NIH/3T3 cell lysate was resolved by electrophoresis, transferred to PVDF membran...
Western Blot Analysis:
Representative lot data.
NIH/3T3 cell lysate was resolved by electrophoresis, transferred to PVDF membranes and prob...
Anti-FUBP3 Antibody
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M, R, Pm, B | WB | Rabbit | Affinity Purified | Polyclonal Antibody |
Description:
Anti-FUBP3 Antibody | 07-742
Promotional Text:
Specificity:
This antibody recognizes FUBP3.
Molecular Weight:
~ 62 kDa
Epitope:
Internal
Immunogen:
KLH-conjugated linear peptide corresponding to human FUBP3.
Background Information:
The three far-upstream element (FUSE) binding proteins (FBP1, FBP2, and FBP3) belong to an ancient family of single-stranded DNA binding proteins which are required for proper regulation of the c-myc proto-oncogene. The FBP, FBP2, and FBP3 genes are located on different chromosomes in mice and humans. However, their primary sequences are closely related. The FPB proteins are believed to be multifunctional. Besides regulating the transcription of c-myc (and quite likely other targets), the FBP family has been shown to bind a variety of RNAs in vitro.
Species Reactivity:
- Human
- Mouse
- Rat
- Primate
- Bovine
Species Reactivity Note:
Demonstrated to react with human, mouse, and rat. Predicted to react with primate and bovine based on 100% sequence homology.
Application Notes:
Western Blot (SNAP ID) Analysis: 2 µg/ml from a representative lot detected FUBP3 on 10 µg of NIH/3T3 cell lysate.
Control:
NIH/3T3 cell lysate
Quality Assurance:
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 0.1 µg/ml of this antibody detected FUBP3 on 10 µg of NIH/3T3 cell lysate.
Western Blot Analysis: 0.1 µg/ml of this antibody detected FUBP3 on 10 µg of NIH/3T3 cell lysate.
Purification Method:
Affinity Purfied
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- FUBP3
- FBP3
Alternate Names:
- FUSE-binding protein 3
- far upstream element (FUSE) binding protein 3
- far upstream element binding protein 3
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.
SUBCELLULAR LOCATION: Nucleus Probable.
TISSUE SPECIFICITY: Detected in a number of cell lines.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SEQUENCE SIMILARITIES: Contains 4 KH domains.
SEQUENCE CAUTION: The sequence AAC50893.1 differs from that shown. Reason: Frameshift at position 18.
The sequence AAH01325.1 differs from that shown. Reason: Frameshift at position 527.
SUBCELLULAR LOCATION: Nucleus Probable.
TISSUE SPECIFICITY: Detected in a number of cell lines.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SEQUENCE SIMILARITIES: Contains 4 KH domains.
SEQUENCE CAUTION: The sequence AAC50893.1 differs from that shown. Reason: Frameshift at position 18.
The sequence AAH01325.1 differs from that shown. Reason: Frameshift at position 527.
Product Name:
Anti-FUBP3 Antibody (07-742)
Concentration:
0.5 mg/mL
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit