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Ordering Information
- : 07-913
- : 100 µg
Product Images
Lysates from Rat testes were probed with anti-STAT4 (1:1,000). Arrow indicates STAT4 (85 kDa).
Anti-STAT4
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| M, R | WB | Rabbit | Affinity Purified | Polyclonal Antibody |
Description:
Anti-STAT4
Trade Name:
Upstate (Millipore)
Specificity:
STAT4
Molecular Weight:
85 kDa
Immunogen:
Synthetic peptide corresponding to the C-terminal region of mouse STAT4
Isotype:
IgG
Species Reactivity:
- Mouse
- Rat
Application Notes:
Suggested dilutions:
Western Blot: 1:1000
Western Blot: 1:1000
Quality Assurance:
Routinely evaluated by immunoblot.
Purification Method:
Immunoaffinity purified
Presentation:
100 μg of immunoaffinity purified rabbit polyclonal IgG in 100 μl of 1X PBS, pH 7.3, 50% glycerol with 1.0 mg/mL BSA and 0.05% Azide.
Storage Conditions:
2 years at -20°C from date of shipment
UniProt Number:
Entrez Gene Number:
Gene Symbol:
STAT4
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: SwissProt: Q14765 # Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
SIZE: 748 amino acids; 85941 Da
SUBUNIT: Forms a homodimer or a heterodimer with a related family member (By similarity). The SH2 domain interacts, in vitro, with IL12RB2 via a short cytoplasmic domain.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
PTM: Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity).
SIMILARITY: SwissProt: Q14765 ## Belongs to the transcription factor STAT family. & Contains 1 SH2 domain.
SIZE: 748 amino acids; 85941 Da
SUBUNIT: Forms a homodimer or a heterodimer with a related family member (By similarity). The SH2 domain interacts, in vitro, with IL12RB2 via a short cytoplasmic domain.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
PTM: Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity).
SIMILARITY: SwissProt: Q14765 ## Belongs to the transcription factor STAT family. & Contains 1 SH2 domain.
Qty/Pk:
100 µg
Brand Family:
Upstate
Format:
Affinity Purified
Host:
Rabbit
Product Name:
Anti-STAT4
Antibody Type:
Polyclonal Antibody