Ordering Information
- : 09-084
- : 100 µg
- : 1 mg/mL
Product Images
Western Blot Analysis:
Representative lot data.
Raji lysate was resolved by electrophoresis, transferred to PVDF and probed with anti-HLX1 (...
Western Blot (SNAP ID) Analysis:
Lysates was resolved by
electrophoresis, transferred to PVDF and probed with anti-HLX1.
Proteins w...
Anti-HLX1 Antibody
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M, R | WB | Rabbit | Affinity Purified | Polyclonal Antibody |
Description:
Anti-HLX1 Antibody | 09-084
Promotional Text:
Specificity:
This antibody recognizes HLX1.
Molecular Weight:
~51 kDa
Immunogen:
KLH conjugated linear peptide corresponding to human HLX1.
Background Information:
HLX1 homeobox protein (H2.0-like homeobox protein) is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. HLX1 is involved in embryogenesis and hematopoiesis and is located in the nucleus. HLX1 can be found at low levels in normal B and T-cells, and at high levels in activated lymphocytes and monocytes. HLX1 can also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain tissue.
Species Reactivity:
- Human
- Mouse
- Rat
Species Reactivity Note:
Demonstrated to react with human, mouse, and rat. Cow (82% sequence homology).
Application Notes:
Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected HLX1 in Western Blot (SNAP ID) Analysis.
Control:
Raji cell lysate
Quality Assurance:
Evaluated by Western Blot in raji cell lysate.
Western Blot Analysis: 0.25 µg/mL of this antibody detected HLX1 in 10 µg of raji cell lysate.
Western Blot Analysis: 0.25 µg/mL of this antibody detected HLX1 in 10 µg of raji cell lysate.
Purification Method:
Affinity Purfied
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable at 2-8°C for 1 year from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- HB24
- HLX1
- OTTHUMP00000035459
- homeobox
Alternate Names:
- H2.0 (Drosophila)-like homeo box 1
- H2.0-like homeo box 1
- H2.0-like homeo box-1
- H2.0-like homeobox
- H2.0-like homeobox 1
- H2.0-like homeobox 1 (Drosophila)
- Homeobox protein HB24
- Homeobox protein HLX1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis By similarity.
SUBCELLULAR LOCATION: Nucleus Potential.
TISSUE SPECIFICITY: Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
SEQUENCE SIMILARITIES: Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.
SEQUENCE CAUTION: The sequence BAD92049.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence BAD92049.1 differs from that shown. Reason: Frameshift at positions 198, 259 and 321.
The sequence M60721 differs from that shown. Reason: Frameshift at positions 69, 115, 152 and 167.
SUBCELLULAR LOCATION: Nucleus Potential.
TISSUE SPECIFICITY: Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
SEQUENCE SIMILARITIES: Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.
SEQUENCE CAUTION: The sequence BAD92049.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence BAD92049.1 differs from that shown. Reason: Frameshift at positions 198, 259 and 321.
The sequence M60721 differs from that shown. Reason: Frameshift at positions 69, 115, 152 and 167.
Product Name:
Anti-HLX1 Antibody (09-084)
Concentration:
1 mg/mL
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 µg
Format:
Affinity Purified
Host:
Rabbit