Bim-GST

Bim-GST

Upstate (Millipore)

100 µg

• Kinase Assay
• Western Blotting

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

FUNCTION: SwissProt: P09211 # Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
SIZE: 210 amino acids; 23356 Da
SUBUNIT: Homodimer.
SIMILARITY: SwissProt: P09211 ## Belongs to the GST superfamily. Pi family.

Mouse

Bim-GST can be phosphorylated by JNK1a1/SAPK1c at residues Ser55 and Ser65 in vitro in both a radioactive and non-radioactive assay.

Upstate

50mM Tris-HCl, pH 8.0, 150mM NaCl, and 20mM glutathione with 20% glycerol

P09211

6 months at -20°C

• GSTP1
• DFN7
• GST3
• FAEES3
• GSTP1-1
• PI

• Apoptosis
• Bioactive Peptides

Bim-GST

NM_000852.2