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Blk, active
Description:
Blk, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
Recombinant full-length mouse Blk, containing an N-terminal His6-tag
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UniProt Summary:
FUNCTION: SwissProt: P51451 # May function in a signal transduction pathway that is restricted to B-lymphoid cells.
SIZE: 505 amino acids; 57706 Da
SIMILARITY: SwissProt: P51451 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
SIZE: 505 amino acids; 57706 Da
SIMILARITY: SwissProt: P51451 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Species:
Mouse
Molecular Weight:
57.7kDa
Quality Assurance:
routinely evaluated by phosphorylation of Poly (Glu4Tyr), biotinylated substrate peptide
Brand Family:
Upstate
Source:
Expressed by baculovirus in Sf21 insect cells
Protein Target:
Blk
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Storage Conditions:
1 year at -70°C
Target Sub-Family:
TK
Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
Packaging:
Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-316M when ordering the 250μg size.
Protein/Isoform Description:
B-lymphoid tyrosine kinase (Blk) is a B-cell specific Src-family (non-receptor) tyrosine kinase, implicated in cancer, whose expression is regulated by the AML-1 protein.
Gene Symbol:
- BLK
- MGC10442
Protein or Enzyme Type:
- Kinases
- Signal Transduction
Product Name:
Blk, active
Entrez Gene Number:
Purification Method:
Ni-NTA agarose