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ARK5, active
Description:
ARK5, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
N-terminal 6His-tagged, recombinant, human ARK5, amino acids 2-end
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UniProt Summary:
FUNCTION: SwissProt: O60285 # Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
COFACTOR: Magnesium.
SIZE: 661 amino acids; 74305 Da
TISSUE SPECIFICITY: Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
SIMILARITY: SwissProt: O60285 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. & Contains 1 protein kinase domain.
COFACTOR: Magnesium.
SIZE: 661 amino acids; 74305 Da
TISSUE SPECIFICITY: Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
SIMILARITY: SwissProt: O60285 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. & Contains 1 protein kinase domain.
Species:
Human
Molecular Weight:
78kDa
Quality Assurance:
Routinely evaluated by phosphorylation of CHKtide
Brand Family:
Upstate
Source:
Expressed by baculovirus in Sf21 cells
Protein Target:
NuaK1 (ARK5)
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Storage Conditions:
Stable for 6 months at -70°C from date of shipment
Target Sub-Family:
CAMK
Gene Symbol:
- NUAK1
- KIAA0537
- ARK5
- NuaK1
Protein or Enzyme Type:
Kinases
Product Name:
ARK5, active
Entrez Gene Number:
Purification Method:
Ni2+/NTA-agarose