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Casein Kinase 2α2, active
Description:
Casein Kinase 2α2, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
N-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UniProt Summary:
FUNCTION: SwissProt: P19784 # Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
SIZE: 350 amino acids; 41213 Da
SUBUNIT: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
SIMILARITY: SwissProt: P19784 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. & Contains 1 protein kinase domain.
SIZE: 350 amino acids; 41213 Da
SUBUNIT: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
SIMILARITY: SwissProt: P19784 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. & Contains 1 protein kinase domain.
Species:
Human
Molecular Weight:
45.8kDa
Quality Assurance:
routinely evaluated by phosphorylation of casein kinase 2 substrate peptide
Brand Family:
Upstate
Source:
expressed by baculovirus in Sf21 cells
Protein Target:
CK2α2
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Storage Conditions:
stable for 6 months at -70°C from date of shipment
Target Sub-Family:
CMGC
Gene Symbol:
- CSNK2A2
- CK2A2
- CSNK2A1
- FLJ43934
Protein or Enzyme Type:
Kinases
Product Name:
Casein Kinase 2α2, active
Entrez Gene Number:
Purification Method:
Ni2+/NTA-agarose