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DAPK1, active
Description:
DAPK1, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.
UniProt Summary:
FUNCTION: SwissProt: P53355 # Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
COFACTOR: Magnesium.
SIZE: 1432 amino acids; 160286 Da
SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with the actin filament system.
SIMILARITY: SwissProt: P53355 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 10 ANK repeats. & Contains 1 death domain. & Contains 1 protein kinase domain.
COFACTOR: Magnesium.
SIZE: 1432 amino acids; 160286 Da
SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with the actin filament system.
SIMILARITY: SwissProt: P53355 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 10 ANK repeats. & Contains 1 death domain. & Contains 1 protein kinase domain.
Species:
Human
Molecular Weight:
60.9kDa
Quality Assurance:
routinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)
Brand Family:
Upstate
Source:
expressed by baculovirus in Sf21 cells
Protein Target:
DAPK1
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Storage Conditions:
stable 6 months at -70°C from date of shipment
Target Sub-Family:
CAMK
Gene Symbol:
- DAPK1
- DAPK
- DKFZp781I035
Protein or Enzyme Type:
Kinases
Product Name:
DAPK1, active
Entrez Gene Number:
Purification Method:
Glutathione agarose affinity chromatography