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Casein Kinase 1γ1, active
Description:
Casein Kinase 1γ1, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
N-terminal 6His-tagged, recombinant, human Casein Kinase 1γ1, amino acids 25-355
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
Casein kinase I is the most abundant serine/threonine kinase in eukaryotic cell extracts. Multiple isoforms of the enzyme exist. The gamma-1 isoform is involved in growth and morphogenesis of eukaryotic cells.[supplied by OMIM]
UniProt Summary:
FUNCTION: SwissProt: Q9HCP0 # Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
SIZE: 422 amino acids; 48511 Da
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: Q9HCP0 ## Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. & Contains 1 protein kinase domain.
SIZE: 422 amino acids; 48511 Da
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: Q9HCP0 ## Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. & Contains 1 protein kinase domain.
Species:
Human
Molecular Weight:
41.9kDa
Quality Assurance:
routinely evaluated by phosphorylation of 200μM KRRRALS(p)VASLPGL
Brand Family:
Upstate
Source:
expressed by baculovirus in Sf21 cells
Protein Target:
CK1γ1
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Storage Conditions:
6 months at -70°C from date of shipment
Target Sub-Family:
CK1
Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
Gene Symbol:
CSNK1G1
Protein or Enzyme Type:
Kinases
Product Name:
Casein Kinase 1γ1, active
Entrez Gene Number:
Purification Method:
Ni2+/NTA-agarose