Brasil
MELK, active
Description:
MELK, active
Trade Name:
Upstate (Millipore)
Qty/Pk:
10 µg
Product Overview:
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag
Background Information:
Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Species:
Human
Molecular Weight:
66 kDa
Quality Assurance:
Routinely evaluated by phosphorylation of KKLNRTLSFAEPG
Brand Family:
Upstate
Source:
Recombinant protein of the human MELK gene expressed by baculovirus in insect cells
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Storage Conditions:
6 months at -70°C
Target Sub-Family:
CAMK
Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
Packaging:
Also available in 250μg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250μg size
Protein/Isoform Description:
Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Gene Symbol:
MELK
Protein or Enzyme Type:
Kinases
Product Name:
MELK, active
Entrez Gene Number:
Alternate Names:
- HPK38
- PK38
- pEg3 kinase
Purification Method:
Purified using glutathione-agarose