Ordering Information
- : 14-927
- : 10 µg
PAK1, active
Description:
PAK1, active
Qty/Pk:
10 µg
Product Overview:
This protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Key Applications:
Kinase Assay
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Species:
Human
Molecular Weight:
46 kDa
Quality Assurance:
Routinely evaluated by phosphorylation of peptide RRRLSFAEPG.
Brand Family:
Upstate
Source:
N-terminal FLAG-tagged, recombinant, human PAK1 amino acids 150-end, expressed by baculovirus in Sf21 insect cells.
Presentation:
50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Protein Target:
PAK1
UniProt Number:
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Target Sub-Family:
STE
Storage Conditions:
6 months at -70°C
Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
Packaging:
Also available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
Gene Symbol:
- PAK1
- Alpha-PAK
- p21-activated kinase 1
- PAK-1
- p65-PAK
Product Name:
PAK1, active
Entrez Gene Number:
Purification Method:
Purified by immunoaffinity chromatography.