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ICC: 2μg/ml of this lot showed positive immunostaining in HeLa cells.
Anti-phospho Ser/Thr-Pro, MPM-2, Texas Red conjugate
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| A | WB, IC | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-phospho Ser/Thr-Pro, MPM-2, Texas Red conjugate
Trade Name:
Upstate (Millipore)
Product Overview:
Specificity:
Recognizes a phosphorylated epitope (S/T)P found in phosphoproteins such as MAP2, HSP70, cdc25, and DNA topoisomerase IIα most of which are phosphorylated at the onset of mitosis. The number of phosphoproteins recognized by MPM-2 varies from species to species and with the cell type.
Immunogen:
Mitotic human HeLa cell cytosolic lysate.
Modifications:
Phosphorylation
Isotype:
IgG1
Species Reactivity:
All
Quality Assurance:
Routinely evaluated by immunoblot on colcemid treated human HeLa carcinoma cells.
Purification Method:
Protein G purfied
Storage Conditions:
1 year at 4°C from date of shipment
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
- Western Blotting
- Immunocytochemistry
Qty/Pk:
50 µg
Brand Family:
Upstate
Format:
Purified
Host:
Mouse
Protein/Isoform Description:
MPM-2 (mitotic protein monoclonal-2) is known industry wide as one of the most versatile phospho-serine/threonine antibodies available because of its ability to recognize more than 40 mitotic phosphoproteins. Upon entry into M (Mitosis) phase, many proteins are phosphorylated either directly or indirectly by M-phase-promoting factor (MPF). Mitotic Protein Monoclonal 2 is an antibody which recognizes a phospho-epitope present in a large number of proteins, primarily during G2 and M phases of the cell cycle. While no true pan-phospho-serine or -threonine antibody has ever been produced, MPM-2 recognizes a wide variety of sites, most proline-directed, and is therefore suitable for the non-radioactive detection of many phospho-serines and -threonines.
Product Name:
Anti-phospho Ser/Thr-Pro, MPM-2, Texas Red conjugate
Antibody Type:
Monoclonal Antibody