Anti-Phosphoserine, clone 4A4, HRP Conjugate
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| A | WB | Mouse | HRP | Monoclonal Antibody |
Description:
Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate | 16-455
Promotional Text:
Trade Name:
Upstate (Millipore)
Molecular Weight:
Varies
Epitope:
phosphoserine
Immunogen:
Phosphoserine conjugated to KLH.
Modifications:
Phosphorylation
Clone:
4A4
Isotype:
IgG1
Background Information:
The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.
Species Reactivity:
All
Species Reactivity Note:
Recognizes proteins containing phosphoserine residues, regardless of origin.
Quality Assurance:
Routinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.
Purification Method:
Protein G purfied
Presentation:
100 μL of protein G purified mouse IgG1 in PBS containing 0.05% ProClin®150 and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.
Storage Conditions:
6 months at 2-8°C from date of shipment.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
UniProt Number:
Entrez Gene Number:
Alternate Names:
- 4A4
- anti-phosphoserine
- phosphoserine antibody
- pan-phosphoserine
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Western Blotting
Brand Family:
Upstate
Product Name:
Anti-Phosphoserine, clone 4A4, HRP Conjugate
Antibody Type:
Monoclonal Antibody
Qty/Pk:
10 blots
Format:
HRP
Host:
Mouse