Bestellinformationen
ApoptoPak™, (anti-Bcl-2, Bak, Bax) Miniature Set
| Speziesreaktivität | Hauptanwendungen | Wirt | Format | Antikörperart |
|---|---|---|---|---|
| H, M | IP, WB, IC, IH | null | null | null |
UniProt-Nummer:
UniProt Summary
FUNCTION: SwissProt: P10415 # Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
SIZE: 239 amino acids; 26266 Da
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SIZE: 239 amino acids; 26266 Da
GenBank-Nummer:
Entrez Gene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also inter
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Description:
ApoptoPak™, (anti-Bcl-2, Bak, Bax) Miniature Set
Key Applications:
- Immunoprecipitation
- Western Blotting
- Immunocytochemistry
- Immunohistochemistry
Species Reactivity:
- Human
- Mouse
Gene Symbol:
- BCL2
- Bcl-2
Quality Assurance:
routinely evaluated by western blot, immunoprecipitation, immunocytochemistry or immunohistochemistry
Components:
- Anti-Bcl-2
- Anti-Bak
- Anti-Bax
Antibody Category:
Apoptosis & Cancer
Antibody Sub-Category:
BCL2 & Inhibition
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Upstate (Millipore)
Kit or Assay Type:
- Apoptosis Assays
- Apoptosis Assays