Guava TUNEL Kit for Flow Cytometry
Description:
Guava TUNEL Kit
Trade Name:
Guava
Qty/Pk:
100 Tests
Product Overview:
Guava TUNEL Assay
for detection of late-stage apoptosis
One of the hallmarks of late stage apoptosis, or programmed cell death, is the fragmentation of nuclear chromatin. The DNA degradation generates DNA strands with exposed 3'-hydroxyl ends.
Quantitative fluorescence assay
The Guava® TUNEL Assay detects apoptosis-induced DNA fragmentation through a quantitative fluorescence assay. Terminal deoxynucleotidyl transferase (TdT) catalyzes the incorporation of bromo-deoxyuridine (BrdU) residues into the fragmenting nuclear DNA at the 3'-hydroxyl ends by nicked end labeling. A TRITC-conjugated anti-BrdU antibody can then label the 3'-hydroxyl ends for detection by a Guava System. For use with all instruments. Click here for more information regarding Instrument Compatibility.
for detection of late-stage apoptosis
One of the hallmarks of late stage apoptosis, or programmed cell death, is the fragmentation of nuclear chromatin. The DNA degradation generates DNA strands with exposed 3'-hydroxyl ends.
Quantitative fluorescence assay
The Guava® TUNEL Assay detects apoptosis-induced DNA fragmentation through a quantitative fluorescence assay. Terminal deoxynucleotidyl transferase (TdT) catalyzes the incorporation of bromo-deoxyuridine (BrdU) residues into the fragmenting nuclear DNA at the 3'-hydroxyl ends by nicked end labeling. A TRITC-conjugated anti-BrdU antibody can then label the 3'-hydroxyl ends for detection by a Guava System. For use with all instruments. Click here for more information regarding Instrument Compatibility.
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Product Name:
Guava TUNEL Kit
Flow Cytometry Market:
- Bioprocess
- Research
Flow Cytometry Research Subcategory:
Late