Guava Express CD3/CD8 Kit

Guava Express CD3/CD8 Kit

Guava

The Guava® Express CD3/CD8™ Reagent Kit is a two-color direct immunofluorescence reagent for enumeration of mature CD8(+) suppressor/cytotoxic T lymphocytes in human blood. The reagent kit consists of an anti-human CD3 antibody conjugated to the tandem dye phycoerythrin (PE)-Cy5(PECy5), an anti-human CD8 antibody conjugated to PE, Guava 1X Lysing Solution to lyse erythrocytes and Guava Fixative to preserve the cells. The CD3 antibody uniquely identifies T cells and recognizes an epitope that is expressed on the epsilon chain of the CD3/T cell antigen receptor (TcR) complex. The CD8 antibody allows the identification of human suppressor/cytotoxic CD8+ T cell and recognizes an antigen expressed on the 32K Da α-subunit of the disulfide linked CD8 biomolecular complex. The cytoplasmic domain of the α-subunit of the CD8 antigen is associated with the protein tyrosine kinase p56 1ck. The CD8 antigen is also present on a subset of natural killer (NK) lymphocytes without the co-expression of CD3 molecule.

Flow Cytometry

Human

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

• 575
• 675

tube;microplate

10ul

Biomarker Detection

Immune Response

HIV Monitoring

• 488
• 532

• Anti-Human CD8-PE Reagent (1 x 0.1 mL)
• Anti-Human CD3-PECy5 Reagent (1 x 0.1 mL)
• Guava Antibody Dilution Buffer (1 x 1 mL)
• Guava 1X Lysing Solution (1 x 20 mL)
• Guava Fixative (1 x 0.5 mL)

Phycoerythrin/Cy5

Fluorescent

• Infectious Diseases
• Inflammation & Immunology

• Research
• Clinical