MILLIPLEX MAP Total p70 S6 Kinase MAPmate - Cell Signaling Single Plex or Multiplex Assay
Description:
MILLIPLEX MAP Total p70 S6 Kinase MAPmate
Trade Name:
MILLIPLEX
Qty/Pk:
1 kit
Applications:
This MILLIPLEX® MAP Total p70 S6 Kinase MAPmate is a Cell Signaling single plex or multiplex assay. The analyte available for this kit is p70 S6 Kinase (Total).
Key Applications:
Multiplexing
Application Notes:
The MILLIPLEX MAP Total p70 S6 Kinase MAPmates pair is used in conjunction with the MILLIPLEX MAP Cell Signaling Buffer and Detection Kit (Catalog # 48-602) to detect the presence of total p70 S6 Kinase in cell lysates using the Luminex® 100 IS, 200, or HTS system.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
UniProt Summary:
FUNCTION: SwissProt: Q9UBS0 # Phosphorylates specifically ribosomal protein S6.
SIZE: 482 amino acids; 53483 Da
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: Q9UBS0 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.
SIZE: 482 amino acids; 53483 Da
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: Q9UBS0 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.
Brand Family:
Upstate
Storage Conditions:
1 year at 4°C
Gene Symbol:
- RPS6KB2
- p70S6Kb
- p70-beta
- P70-beta-2
- S6K-beta2
- p70(S6K)-beta
- P70-beta-1
- KLS
- p70-S6KB
- S6K2
- S6K-beta
- P70-BETA
- SRK
- STK14B
- P70-beta
Product Name:
MILLIPLEX MAP Total p70 S6 Kinase MAPmate
Analytes Available:
p70 S6 Kinase (Total), p70S6
Configuration:
Single Plex
Components:
- Anti-p70 S6 Kinase Beads
- Anti-p70 S6 Kinase, Biotin
UniProt Number:
Panel Type:
Cell Signaling
Detection Methods:
- Fluorescent
- Luminex xMAP
Packaging:
100 assay points
Entrez Gene Number: