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  • : 46-670
  • : 1 kit
  • Product Family Information

MILLIPLEX MAP Phospho MEK1 (Ser222) MAPmate - Cell Signaling Single Plex or Multiplex Assay

Description:
MILLIPLEX MAP Phospho MEK1 (Ser222) MAPmate
Trade Name:
MILLIPLEX
Qty/Pk:
1 kit
Applications:
This MILLIPLEX® MAP Phospho MEK1 (Ser222) MAPmate is a Cell Signaling single plex or multiplex assay. The analyte available for this kit is MEK1 (Ser222).
Key Applications:
Multiplexing
Application Notes:
The MILLIPLEX MAP Phospho MEK1 (Ser222) MAPmates pair is used in conjunction with the MILLIPLEX MAP Cell Signaling Buffer and Detection Kit (Catalog # 48-602) to detect the presence of phosphorylated MEK1 (Ser222) in cell lysates using the Luminex® 100™ IS, 200™, or HTS system.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
UniProt Summary:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
Brand Family:
Upstate
Storage Conditions:
Recommended storage for kit components is 2 - 8°C
Modifications:
Phosphorylation
Product Name:
MILLIPLEX MAP Phospho MEK1 (Ser222) MAPmate
Analytes Available:
MEK1 (Ser222)
Configuration:
Single Plex
Components:
  • Anti-phospho MEK1 (Ser222) Beads
  • Anti- phospho MEK1 (Ser222), biotin
  • A431 Cell Lysate: EGF stimulated
UniProt Number:
Q02750
Panel Type:
Cell Signaling
Detection Methods:
  • Luminex xMAP
  • Fluorescent
Packaging:
100 assay points
Entrez Gene Number:
NM_002755