MILLIPLEX MAP Human Phospho-Histone H2A.X (SER139) MAPmate

MILLIPLEX MAP Human Phospho-Histone H2A.X (SER139) MAPmate

MILLIPLEX

Histone, H2A, H2B, H3, H4 are all involved in chromatin packing, organization, regulation and memory. One function of H2A.X is to signal the maintenance of a cll cycle arrest until repair is completed because it is rapidly phosphorylated at Ser¹³⁹ by the atazia-telangiectasia mutated (ATM) kinase in response to DNA double-strand breaks. The accumulation of high levels of H2A.X phosphorylation is a very early and accurate indicator of apoptosis.

Multiplexing

The MILLIPLEX MAP Phospho-Histone H2A.X (SER139) MAPmate pair is used in conjunction with the MILLIPLEX MAP Cell Signaling Buffer and Detection Kit (Catalog # 48-602) to detect the presence of phosphorylated Histone H2A.X (SER139) in cell lysates using the Luminex® 100 IS, 200, or HTS system.

Human

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

• Cell Signaling Kits
• Cancer Kits
• Multiplex Assays

Oncology

• Anti-Histone H2A.X MILLIPLEX MAP
• Anti-Phosopho-Histone H2A.X (Ser139)

Cell Signaling

Luminex xMAP

100 points

H2A.X (Ser139)