MILLIPLEX MAP Total BAD MAPmate
Description:
MILLIPLEX MAP Total BAD MAPmate
Trade Name:
MILLIPLEX
Product Overview:
Apoptosis, programmed cell death, is a tightly controlled process involved in both embryonic development and adult homeostasis in which the body is able to rid itself of damaged or unnecessary cells without inducing an inflammatory response. This essential process is triggered by both internal (DNA damage, mitochondrial dysfunction) and external (Fas and TNF receptor) signals. Dysregulated apoptosis that results in accelerated programmed cell death has been implicated in the development of various neurological diseases, such as Alzheimer’s and Parkinson’s disease, while inhibition of apoptosis is involved in the development of autoimmune disorders and cancer.
Key Applications:
Multiplexing
Application Notes:
The MILLIPLEX MAP Total BAD MAPmates pair is used in conjunction with the MILLIPLEX MAP Cell Signaling Buffer and Detection Kit (Catalog # 48-602) to detect the presence of total BAD in cell lysates using the Luminex® 100 IS, 200, or HTS system.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Kit or Assay Type:
- Cancer Kits
- Cell Signaling Kits
- Multiplex Assays
Therapeutic Areas:
Oncology
Components:
- Anti-BAD Beads
- Anti-BAD, biotin
Panel Type:
Cell Signaling
Detection Methods:
Luminex xMAP
Packaging:
100 points
Gene Symbol:
- BAD
- BBC2
- BBC6
- BCL2L8
Array Type:
Antibody Arrays
Materials Required but Not Delivered:
Assay Buffer 1 (43-010)
Universal Lysis Buffer (43-040)
Beadlyte cell signaling streptavidin-phycoerythrin (45-0001D)
Milllipore 96-well filter plate (40-0008)
Universal Lysis Buffer (43-040)
Beadlyte cell signaling streptavidin-phycoerythrin (45-0001D)
Milllipore 96-well filter plate (40-0008)
Analytes Available:
BAD (Total)


