Ordering Information
- : 569397-1MG
- : 1 MG
Staurosporine, Streptomyces sp. | Calbiochem | CAS 62996-74-1 | 1MG
Description:
Staurosporine, Streptomyces sp. | Calbiochem | CAS 62996-74-1 | 1MG
Trade Name:
Calbiochem (EMD Millipore)
Qty/Pk:
1 MG
Background Information:
A potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A (IC50 = 7 nM), CaM kinase (IC50 = 20 nM), myosin light chain kinase (IC50 = 1.3 nM), protein kinase C (IC50 = 700 pM), and protein kinase G (IC50 = 8.5 nM). Also inhibits platelet aggregation induced by collagen or ADP but has no effect on thrombin-induced platelet aggregation. Induces apoptosis in human malignant glioma cell lines. Arrests normal cells at the G1 checkpoint. A 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 569396) in DMSO is also available.
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Molecular Weight:
466.5
CAS No.:
62996-74-1
Brand Family:
Calbiochem
Presentation:
Pale yellow solid. Packaged under inert gas.
UniProt Number:
Storage Conditions:
Shipped at Ambient Temperature. Store at +2 - 8°C.
Properties:
Solubility: DMSO (5 mg/ml). Further dilute with aqueous buffers just prior to use.
Gene Symbol:
MYLK
PubChem ID:
26759562
Product Name:
Staurosporine, Streptomyces sp. | Calbiochem | CAS 62996-74-1 | 1MG
Entrez Gene Number:
Empirical Formula:
C28H26N4O3
Alternate Names:
MLCK Inhibitor I