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Ordering Information
- : AB3454
- : 100 µg
- : 0.5 mg/mL
Anti-ACT, N-terminus
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | ELISA, WB | Rabbit | Purified | Polyclonal Antibody |
Description:
Anti-ACT, N-terminus
Trade Name:
Chemicon (Millipore)
Specificity:
ACT (Activator of CREM in testis), N terminus.
Epitope:
N-terminus
Immunogen:
N-terminus of human ACT protein
Background Information:
Transcriptional activation of CREB and CREM are required for proper cellular differentiation. A novel protein, activator of CREM in testis (ACT) is expressed
Species Reactivity:
Human
Application Notes:
Immunoblotting: 1:500-1:1,000
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Presentation:
Liquid. Buffer = PBS containing 0.02% sodium azide
Storage Conditions:
Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- FHL5
- FHL-5
- FLJ33049
- dJ393D12.2
- KIAA0776
- ACT
- 1700027G07Rik
- RP3-393D12.2
Alternate Names:
Activator of CREM in Testis
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene.
Key Applications:
- ELISA
- Western Blotting
UniProt Summary:
FUNCTION: SwissProt: Q5TD97 # May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation- independent manner.
SIZE: 284 amino acids; 32720 Da
SUBUNIT: Interacts with CREM via the third LIM domain (By similarity).
SUBCELLULAR LOCATION: Nucleus. Note=Nuclei of round and elongated spermatids.
TISSUE SPECIFICITY: Testis-specific (at protein level).
SIMILARITY: SwissProt: Q5TD97 ## Contains 4 LIM zinc-binding domains.
SIZE: 284 amino acids; 32720 Da
SUBUNIT: Interacts with CREM via the third LIM domain (By similarity).
SUBCELLULAR LOCATION: Nucleus. Note=Nuclei of round and elongated spermatids.
TISSUE SPECIFICITY: Testis-specific (at protein level).
SIMILARITY: SwissProt: Q5TD97 ## Contains 4 LIM zinc-binding domains.
Qty/Pk:
100 µg
Brand Family:
Chemicon
Format:
Purified
Host:
Rabbit
Product Name:
Anti-ACT, N-terminus
Concentration:
0.5 mg/mL
Antibody Type:
Polyclonal Antibody