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Ordering Information
- : AB3861
- : 200 µL
Anti-UbcH10
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | IP, WB | Rabbit | Affinity Purified | Polyclonal Antibody |
Description:
Anti-UbcH10
Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes UbcH10.
Immunogen:
Full length, highly purified, UbcH10 protein.
Background Information:
UbcH10 in conjunction with the anaphase-promoting complex catalyzes the destruction of cyclins A and B and therefore plays an important role in the control of the cell exit from mitosis.
Species Reactivity:
Human
Application Notes:
Western blot: 1:100-1:1000
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Presentation:
Protein A purified immunoglobulin in PBS, pH 7.4.
Storage Conditions:
Maintain at -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. May be stored at 2-8°C for up to 1 month.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- UBE2C
- UBCH10
- dJ447F3.2
- UbcH10
- UBE2C-PEN
- EC 6.3.2.19
Alternate Names:
Ubiquitin-protein Ligase C; Ubiquitin Carrier Protein C; Ubiquitin-conjugating Enzyme E2 C
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Key Applications:
- Immunoprecipitation
- Western Blotting
UniProt Summary:
FUNCTION: SwissProt: O00762 # Catalyzes the covalent attachment of ubiquitin to other proteins. Required for the destruction of mitotic cyclins.
SIZE: 179 amino acids; 19652 Da
SIMILARITY: SwissProt: O00762 ## Belongs to the ubiquitin-conjugating enzyme family.
SIZE: 179 amino acids; 19652 Da
SIMILARITY: SwissProt: O00762 ## Belongs to the ubiquitin-conjugating enzyme family.
Qty/Pk:
200 µL
Brand Family:
Chemicon
Format:
Affinity Purified
Host:
Rabbit
Product Name:
Anti-UbcH10
Antibody Type:
Polyclonal Antibody