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Ordering Information
- : CBL468F
- : 100 assays
Anti-PECAM-1, clone HC1/6, FITC conjugated
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC | Mouse | FITC | Monoclonal Antibody |
Description:
Anti-PECAM-1, clone HC1/6, FITC conjugated
Trade Name:
Chemicon (Millipore)
Specificity:
The antibody reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Immunogen:
PMA - treated U937 cells
Clone:
HC1/6
Isotype:
IgG1
Species Reactivity:
Human
Application Notes:
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis
Suitable for direct staining in flow cytometry
Optimal working dilutions must be determined by the end user.
Suitable for direct staining in flow cytometry
Optimal working dilutions must be determined by the end user.
Presentation:
The conjugate is supplied as a 100 test/1mL vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
Storage Conditions:
Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- PECAM1
- EndoCAM
- GPIIA'
- PECAM-1
- CD31
- CD31/EndoCAM
Alternate Names:
CD31
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Flow Cytometry
UniProt Summary:
FUNCTION: SwissProt: P16284 # This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
SIZE: 738 amino acids; 82536 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
PTM: Phosphorylated on Ser and Tyr residues after cellular activation.
SIMILARITY: SwissProt: P16284 ## Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
SIZE: 738 amino acids; 82536 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
PTM: Phosphorylated on Ser and Tyr residues after cellular activation.
SIMILARITY: SwissProt: P16284 ## Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Qty/Pk:
100 assays
Brand Family:
Chemicon
Format:
FITC
Host:
Mouse
Product Name:
Anti-PECAM-1, clone HC1/6, FITC conjugated
Antibody Type:
Monoclonal Antibody