Product Images
Flow Cytometry Analysis:
FC analysis using untreated HeLa cells stained with Anti-Sp1 FITC antibody (green) or isotype control antibody (gray).
Milli-Mark™ Anti-Sp1-FITC
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC | Rabbit | FITC | Polyclonal Antibody |
Description:
Milli-Mark™ Anti-Sp1-FITC
Trade Name:
Milli-Mark
Specificity:
Antibody recognizes Human Sp1.
Molecular Weight:
80.7 kDa Calculated
Immunogen:
Recombinant Protein corresponding to Human Sp1.
Isotype:
IgG
Background Information:
Sp1 is a human transcription factor involved in gene expression in the early development of an organism. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA and enhances gene transcription. Sp1 has always been described as a ubiquitous transcription factor that is required for the constitutive and inducible expression of a variety of genes, such as in cell cycle or mammalian development.
Species Reactivity:
Human
Species Reactivity Note:
Tested and passed on Human. Uncojugated version (Cat. No. 07-645) is known to recognize Mouse and Rat.
Control:
HeLa cells.
Quality Assurance:
Evaluated by flow cytometry using HeLa cells.
Purification Method:
Protein A Purified
Presentation:
Purified rabbit polyclonal IgG conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
TSFP1
Alternate Names:
- Sp1 transcription factor
- specificity protein 1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Flow Cytometry
UniProt Summary:
FUNCTION: SwissProt: P08047 # Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.
SIZE: 785 amino acids; 80693 Da
SUBUNIT: Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr.
SUBCELLULAR LOCATION: Nucleus.
PTM: O-glycosylated; contains N-acetylglucosamine side chains.
SIMILARITY: SwissProt: P08047 ## Belongs to the Sp1 C2H2-type zinc-finger protein family. & Contains 3 C2H2-type zinc fingers.
SIZE: 785 amino acids; 80693 Da
SUBUNIT: Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr.
SUBCELLULAR LOCATION: Nucleus.
PTM: O-glycosylated; contains N-acetylglucosamine side chains.
SIMILARITY: SwissProt: P08047 ## Belongs to the Sp1 C2H2-type zinc-finger protein family. & Contains 3 C2H2-type zinc fingers.
Protein/Isoform Description:
Sp1 is a human transcription factor involved in gene expression in the early development of an organism. The protein is 785 amino acids long, with a molecular weight of 95 kDA. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA and enhances gene transcription. Sp1 has always been described as a ubiquitous transcription factor that is required for the constitutive and inducible expression of a variety of genes, such as in cell cycle or mammalian development.
Product Name:
Milli-Mark™ Anti-Sp1-FITC
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 tests
Format:
FITC
Host:
Rabbit