Product Images
Flow Cytometry Analysis:
Representative lot data.
FACS analysis using MCF-7 cells, stained with anti-Retinoid X Receptor alpha antibody (g...
Milli-Mark™ Anti-Retinoid X Receptor α, clone 4E9, FITC Conjugate
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC | Mouse | FITC | Monoclonal Antibody |
Description:
Milli-Mark™ Anti-Retinoid X Receptor α Antibody, clone 4E9, FITC Conjugate | FCMAB123F
Promotional Text:
Trade Name:
Milli-Mark
Specificity:
Antibody recognizes Retinoid X Receptor alpha.
Molecular Weight:
51 kDa Observed
Epitope:
Unknown
Immunogen:
GST - Tagged - Recombinant Protein corresponding to Retinoid X Receptor alpha.
Clone:
4E9
Isotype:
IgG2aκ
Background Information:
Retinoid X receptor α (RXRA or RXR alpha) is a nuclear receptor that mediates the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. RXRs as a whole exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulate their transcription.
Species Reactivity:
Human
Species Reactivity Note:
Tested and passed on Human.
Control:
MCF-7 cells.
Quality Assurance:
Evaluated by flow cytometry using MCF-7 cells.
Purification Method:
Protein G purfied
Presentation:
Purified mouse monoclonal IgG2a conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
FLJ00280
FLJ00318
FLJ16020
FLJ16733
MGC102720
NR2B1
OTTHUMP00000022510
FLJ00318
FLJ16020
FLJ16733
MGC102720
NR2B1
OTTHUMP00000022510
Alternate Names:
Nuclear receptor subfamily 2 group B member 1
Retinoid X receptor alpha
retinoid X receptor, alpha
Retinoid X receptor alpha
retinoid X receptor, alpha
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Flow Cytometry
Entrez Gene Summary:
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. [provided by RefSeq].
UniProt Summary:
FUNCTION: Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer By similarity.
SUBUNIT STRUCTURE: Homodimer or forms a heterodimer with peroxisome proliferator activated receptor gamma called adipocyte-specific transcription factor ARF6. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts with FAM120B By similarity. Interacts with SFPQ. Interacts with HCV core protein. Interacts with PELP1. Interacts with SENP6. Interacts with DNTTIP2. Interacts with RNF8.
SUBUNIT STRUCTURE: Homodimer or forms a heterodimer with peroxisome proliferator activated receptor gamma called adipocyte-specific transcription factor ARF6. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts with FAM120B By similarity. Interacts with SFPQ. Interacts with HCV core protein. Interacts with PELP1. Interacts with SENP6. Interacts with DNTTIP2. Interacts with RNF8.
Product Name:
Milli-Mark™ Anti-Retinoid X Receptor α, clone 4E9, FITC Conjugate
Concentration:
0.5 mg/mL
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 tests
Format:
FITC
Host:
Mouse