Product Images
Flow Cytometry Analysis:
Representative lot data.
FACS analysis using HeLa cells, stained with anti-RBMS1 antibody (green), or Biolegend #...
Milli-Mark™ Anti-RBMS1, clone 4D11, FITC Conjugate
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M | FC | Mouse | FITC | Monoclonal Antibody |
Description:
Milli-Mark™ Anti-RBMS1 Antibody, clone 4D11, FITC Conjugate | FCMAB125F
Promotional Text:
Trade Name:
Milli-Mark
Specificity:
Antibody recognizes RBMS1.
Molecular Weight:
50kDa Observed
Epitope:
Unknown
Immunogen:
GST - Tagged - Recombinant Protein corresponding to RBMS1.
Clone:
4D11
Isotype:
IgG2bκ
Background Information:
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1 or MSSP-1) is a single-stranded DNA binding protein that is characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. At the developmental stage, RBMS1 (MSSP-1) is expressed at its highest levels during the G1 to S transition of the cell cycle and is most commonly found in placenta, lung and heart tissue. RBMS1 (MSSP-1) has been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.
Species Reactivity:
- Human
- Mouse
Species Reactivity Note:
Tested and passed on Human. Unconjugated antibody shown to work in mouse using ICC.
Application Notes:
| Working Solution | Cells / test | Total Reaction Volume |
|---|---|---|
| 5 μl | 5 x 105 Cells / 95 μl PBS | 100 μl |
| 10 μl | 1 x 106 Cells / 90 μl PBS | 100 μl |
Control:
HeLa cells.
Quality Assurance:
Evaluated by flow cytometry using HeLa cells.
Purification Method:
Protein G purfied
Presentation:
Purified mouse monoclonal IgG2b conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
MGC15146
MGC3331
MSSP
MSSP-1
MSSP-2
MSSP-3
MSSP1
SCR2
YC1
MGC3331
MSSP
MSSP-1
MSSP-2
MSSP-3
MSSP1
SCR2
YC1
Alternate Names:
RNA binding motif, single stranded interacting protein 1
Single-stranded DNA-binding protein MSSP-1
Suppressor of CDC2 with RNA-binding motif 2
c-myc gene single strand binding protein 2
suppressor of cdc 2 (cdc13) with RNA binding motif 2
Single-stranded DNA-binding protein MSSP-1
Suppressor of CDC2 with RNA-binding motif 2
c-myc gene single strand binding protein 2
suppressor of cdc 2 (cdc13) with RNA binding motif 2
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.
Key Applications:
Flow Cytometry
UniProt Summary:
FUNCTION: Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.
Product Name:
Milli-Mark™ Anti-RBMS1, clone 4D11, FITC Conjugate
Concentration:
0.5 mg/mL
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 tests
Format:
FITC
Host:
Mouse