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Flow Cytometry Analysis:
Representative lot data.
FACS analysis of anti-human CD19-APC stained human lymphocytes. Cells expressing CD19 (...
Milli-Mark™ Anti-CD19 -APC, clone HD37
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC | Mouse | Purified | Monoclonal Antibody |
Description:
Milli-Mark™ Anti-CD19 -APC, clone HD37
Trade Name:
Milli-Mark
Specificity:
Antibody recognizes Human CD19 antigen.
Molecular Weight:
120 kDa (Pezzutto, 1987; Sato, 1997)
Immunogen:
Hairy cell leukemia cells
Clone:
HD37
Isotype:
IgG1κ
Background Information:
CD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
Species Reactivity:
Human
Species Reactivity Note:
Human
Control:
Human Lymphocytes
Quality Assurance:
Evaluated by flow cytometry using Human Lymphocytes
Purification Method:
Protein A purfied
Presentation:
Purified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Storage Conditions:
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
UniProt Number:
Entrez Gene Number:
Alternate Names:
-
Differentiation antigen CD19
B-lymphocyte surface antigen B4
T-cell surface antigen Leu-12 - B-lymphocyte antigen CD19
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Flow Cytometry
Product Name:
Milli-Mark™ Anti-CD19 -APC, clone HD37
Concentration:
0.075 mg/mL
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 tests
Format:
Purified
Host:
Mouse