Ordering Information
- : FCMAB407F
- : 100 tests
Product Images
Flow Cytometry Analysis:
Representative lot data.
FC analysis of HEK293T cells stained with either anti-Erythropoietin FITC (green) antibo...
Milli-Mark® Anti-Erythropoietin-FITC, clone 1C8
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC | Mouse | FITC | Monoclonal Antibody |
Description:
Milli-Mark® Anti-Erythropoietin-FITC, clone 1C8
Specificity:
Antibody recognizes Human Erythropoietin.
Molecular Weight:
21 kDa Calculated
Immunogen:
Recombinant human Erythropoietin
Clone:
1C8
Isotype:
IgG2b
Background Information:
Erythropoietin (Epo) is a glycoprotein consisting of one 165-amino acid single-chain polypeptide with two internal disulfide bonds. When fully glycosylated, the molecular weight of Epo is approximately 34 kDa. Normally produced by the liver and kidney, Epo is the principle regulator of red blood cell production by stimulating the division and differentiation of bone marrow erythroid progenitor cells in response to anemia and hypoxia.
Species Reactivity:
Human
Species Reactivity Note:
Tested and passed on Human.
Control:
HEK293 cells
Quality Assurance:
Evaluated by flow cytometry using HEK293 cells.
Purification Method:
Protein A Purified
Presentation:
Purified mouse monoclonal IgG2b conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- EPO
- MGC138142
- EP
Alternate Names:
- erythropoietin
- Epoetin
- epoetin
- EPO
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications:
Flow Cytometry
Entrez Gene Summary:
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
UniProt Summary:
FUNCTION: SwissProt: P01588 # Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
SIZE: 193 amino acids; 21307 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
SIMILARITY: SwissProt: P01588 ## Belongs to the EPO/TPO family.
SIZE: 193 amino acids; 21307 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
SIMILARITY: SwissProt: P01588 ## Belongs to the EPO/TPO family.
Product Name:
Milli-Mark® Anti-Erythropoietin-FITC, clone 1C8
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 tests
Format:
FITC
Host:
Mouse