Granulocyte Colony-Stimulating Factor, recombinant human
Description:
Granulocyte Colony-Stimulating Factor, recombinant human
Trade Name:
Chemicon (Millipore)
Product Overview:
Granulocyte Colony-Stimulating Factor (G-CSF) is a potent stimulatory of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. Human G-CSF is an 18.7 kDa protein containing 174 amino acid residues.
Key Applications:
Cell Culture
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Alternate Names:
G-CSF
Cell Culture Reagent Type:
Cytokines & Growth Factors
Descriptive Text:
Stem Cell Workflow Stage:
- Maintenance & Expansion
- Differentiation
- General Cell Culture
Gene Symbol:
- CSF3
- Lenograstim
- filgrastim
- Filgrastim
- lenograstim
- MGC45931
- Pluripoietin
- G-CSF
- pluripoietin
- GCSF
Protein Type:
Growth Factor
Presentation:
Lyophilized from 5 mM Sodium Citrate, pH4.0.
Stem Cell Type:
Hematopoietic Stem Cells
Purity:
Greater than 98% by SDS-PAGE
Protein or Enzyme Type:
Cytokines & Growth Factors
Specific Activity:
GF051 is fully biologically active when compared to standards. The ED(50) was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is <=0.1 ng/ml, corresponding to a specific activity of >=1x107 units/mg.
Species:
Human
Storage Conditions:
The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute with sterile water to a concentration of 0.1-0.5 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted GF051 should be stored in working aliquots at -20°C for up to 6 months. Further dilutions should be made into buffer containing carrier protein or medium containing serum.
Source:
E.coli