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  • : HCCBP3MAG-58K
  • : 96-well plate

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Cancer Biomarkers Across Tumor Types

Cancer Biomarkers Across Tumor Types

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MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3, HCCBP3MAG-58K

Number of Analytes Available Detection Methods
9 Luminex xMAP
Description:
MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3, HCCBP3MAG-58K
Trade Name:
MILLIPLEX
Qty/Pk:
96-well plate
Product Overview:
MILLIPLE XMAP Circulating Cancer Biomarker Magnetic Bead Panel 3 consists of 9 circulating cancer biomarkers that can be used to study a wide range of tumor types.
Background Information:
Cancer research has always focused on intracellular biomarkers, such as HER2 and B-Raf, and in recent years, more and more attention has shifted to include extracellular cancer biomarkers. While the use of intracellular markers in research helps clarify the process of oncogenesis, circulating cancer biomarkers give insight into how the body responds to the presence of a tumor, the dysregulation of homeostasis and the relationship between a tumor and its environment. Study of isolated biomarkers, whether intracellular or circulating, is often inadequate to fully characterize the complex relationship between tumor and non-tumor. Consequently, multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
Key Applications:
Multiplexing
Application Notes:
• This is an overnight incubation assay requiring 25 µL of 1:50 dilution plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary).
• This kit may be used for the analysis of all or any combination of the cancer biomarkers in serum, plasma or tissue/cell lysate and culture.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Configuration:
Design your multiplex kit by choosing from 9 analytes.
Sensitivity:
Refer to kit protocol for sensitivities of individual biomarkers.
Storage Conditions:
Recommended storage for kit components is 2 - 8°C.
Precision, %:
  • Intra Assay: 5 - 8
  • Inter Assay: 5 - 17
Accuracy:
74% - 126%
Detection Methods:
Luminex xMAP
Array Type:
Multiplexing
Cross Reactivity:
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Product Name:
MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3, HCCBP3MAG-58K
Standard Curve Range:
  • 0.07 - 50 ng/mL: Catalase, Fibroblast Activation Protein α
  • 0.27 - 200 ng/mL: Cathepsin D, IGFBP3
  • 0.03 - 25 ng/mL: Ferritin
  • 0.004 - 3 ng/mL: Galectin-3
  • 0.1 - 75 ng/mL: Melanoma Inhibitory Activity Protein
  • 0.02 - 20 ng/mL: Myeloperoxidase
  • 0.03 - 25 nM: Sex Hormone Binding Globulin*

    *SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard
Assay Panel:
Everything you need in a single kit.
Analytes Available:
Catalase, Cathepsin D, Ferritin, Fibroblast Activation Protein, Galectin-3, IGFBP-3, Melanoma Inhibitory Activation Protein, Myeloperoxidase, Sex Hormone Binding Globulin

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