Ordering Information
- : IF014
- : 100000 units
- : 1 x 106 units/mL
Interferon-β, recombinant human
Recommended Replacement for: IF008Description:
Interferon-β, recombinant human
Trade Name:
Chemicon (Millipore)
Qty/Pk:
100000 units
Product Overview:
Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a). Molecular weight is ~23 kDa.
Key Applications:
Cell Culture
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
UniProt Summary:
FUNCTION: SwissProt: P01574 # Has antiviral, antibacterial and anticancer activities.
SIZE: 187 amino acids; 22294 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P01574 ## Belongs to the alpha/beta interferon family.
SIZE: 187 amino acids; 22294 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P01574 ## Belongs to the alpha/beta interferon family.
Species:
Human
Brand Family:
Chemicon
Source:
cDNA obtained from human fibroblast mRNA expressed in CHO cells.
Presentation:
Frozen liquid in 50 mM NaOAc, pH 5.5, containing 0.1% BSA.
UniProt Number:
Specific Activity:
SPECIFIC ACTIVITY: 3.99 x 108 units/mg
BIOACTIVITY: Determined by assaying inhibition of virus-induced cytopathic effect. In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for human interferon beta (Hu-IFNbeta) provided by the National Institutes of Health. Unit of activity measured on VERO cells with vesicular stomatitis virus (VSV).
BIOACTIVITY: Determined by assaying inhibition of virus-induced cytopathic effect. In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for human interferon beta (Hu-IFNbeta) provided by the National Institutes of Health. Unit of activity measured on VERO cells with vesicular stomatitis virus (VSV).
Storage Conditions:
After receipt, this product should be kept at -70°C or below for retention of full activity.
Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Cell Culture Reagent Type:
Cytokines & Growth Factors
Replaces:
IF008
Gene Symbol:
- IFNB1
- IFN-beta
- IFF
- IFB
- IFNB
- MGC96956
Protein or Enzyme Type:
Cytokines & Growth Factors
Product Name:
Interferon-β, recombinant human
Entrez Gene Number:
Alternate Names:
Fibroblast Interferon
Concentration:
1 x 106 units/mL
Purity:
> / = 95%, one N-glycosylation site