Interleukin-1α, recombinant human
Description:
Interleukin-1α, recombinant human
Trade Name:
Chemicon (Millipore)
Product Overview:
Interleukin-1alpha is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses. Human IL-1alpha is a 18.0 kDa protein containing 159 amino acid residues.
Key Applications:
Cell Culture
Application Notes:
For most in vitro applications, IL-1alpha exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): Leukocytes.
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Alternate Names:
IL-1alpha
Cell Culture Reagent Type:
Cytokines & Growth Factors
Descriptive Text:
Gene Symbol:
- IL1A
- IL1-ALPHA
- IL1
- pro-interleukin-1-alpha
- IL1F1
- Hematopoietin-1
- IL-1A
- hematopoietin-1
Protein Type:
Active Protein
Presentation:
Lyophilized from 10 mM Tris, pH 8.0, containing 50 mM NaCl.
Purity:
Greater than 98% by SDS-PAGE and HPLC analyses.
Protein or Enzyme Type:
Cytokines & Growth Factors
Specific Activity:
Human IL-1alpha is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of mouse D10S cells is less than 0.001 ng/mL, corresponding to a specific activity of >=1 x 10(E9) units/mg.
Species:
Human
Storage Conditions:
The lyophilized powder, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other buffered solutions or stored at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles.