订购信息
Anti-Glial Fibrillary Acidic Protein, clone GA5, Alexa Fluor® 488 conjugated
| 种属反应性 | 关键应用 | 宿主 | 形式 | 抗体类型 |
|---|---|---|---|---|
| Ch, H, Po, R | IC, IH | Mouse | AlexaFluor®488 | Monoclonal Antibody |
UniProt序列号:
UniProt Summary
FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander diseas ... 更多信息 »
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander diseas ... 更多信息 »
GenBank序列号:
Entrez Gene Summary
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined.
Description:
Anti-Glial Fibrillary Acidic Protein, clone GA5, Alexa Fluor® 488 conjugated
Alternate Names:
GFAP
Specificity:
The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (1).
Key Applications:
- Immunocytochemistry
- Immunohistochemistry
Application Notes:
Immunocytochemistry
Immunohistochemistry
Optimal working dilutions must be determined by end user.
Immunohistochemistry
Optimal working dilutions must be determined by end user.
Species Reactivity:
- Chicken
- Human
- Pig
- Rat
Isotype:
IgG1
Immunogen:
Purified glial filament (1).
Presentation:
Purified immunoglobulin conjugated to Alexa Fluor® 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8°C in the dark for up to 6 months after date of receipt.
Gene Symbol:
- GFAP
- FLJ45472
Antibody Category:
Neuroscience
Antibody Sub-Category:
Neuronal & Glial Markers
Usage Statement:
- Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Chemicon (Millipore)
Format:
AlexaFluor®488
Host:
Mouse
Concentration:
1 mg/mL
Antibody Type:
Monoclonal Antibody