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Ordering Information
- : MAB5740
- : 100 µg
- : 1.0 mg/mL
Product Images
This lot detected Radial Glial Cell Marker-2 at 1:50 to 1:500 dilution in paraffin embedded mouse embryo brain.
Immunohistochemistry Analysis:
Radial Glial Cell Marker-2 representative staining pattern/morphology in developing mouse embryo’s brain. Tissue ...
Anti-Radial Glial Cell Marker-2, clone RC2
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| M | IH | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-Radial Glial Cell Marker-2, clone RC2
Clone:
RC2
Qty/Pk:
100 µg
Background Information:
The monoclonal antibody Radial Glial Cell Marker-2, clone RC2 (RC2) was generated in mouse by conventional hybridoma methodology. The antigen recognized by RC2 is robust, allowing aldehyde fixation appropriate to high resolution light and electron microscopic analyses. From the neural tube stage of fetal development the antibody delineates throughout the central nervous system a subpopulation of neuroepithelial cells which have a radial bipolar morphology. RC2 also recognizes monopolar cell forms in the spinal cord and the cerebellum as early as E15, and in the dentate gyrus of the hippocampal formation from the day of birth. Monopolar forms in the cerebellum are inferred to be progenitors of Bergmann glia. The robustness of the antigen recognized by RC2 makes this probe a valuable tool to study the morphological transformations of the bipolar radial glia during their mitotic turnover. It also provides a sensitive stain for the study of the organization and the histogenetic role of the overall radial fiber system (3).
Key Applications:
Immunohistochemistry
Species Reactivity:
Mouse
Species Reactivity Note:
Mouse. Other species have not been tested.
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen:
Embryonic rat brain
Format:
Purified
Presentation:
Ammonium sulfate purified mouse monoclonal in PBS with 0.05% NaN3.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
Host:
Mouse
Isotype:
IgMλ
Product Name:
Anti-Radial Glial Cell Marker-2, clone RC2
Concentration:
1.0 mg/mL
Antibody Type:
Monoclonal Antibody
Purification Method:
Ammonium sulfate precipitation
Specificity:
Detects radial glial cell marker-2