ApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Kit
Description:
ApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Kit
Trade Name:
- ApopTag
- Chemicon (Millipore)
Qty/Pk:
40 assays
Product Overview:
The ApopTag® Peroxidase In Situ Oligo Ligation Kit specifically detects apoptosis by staining only cells that contain double-stranded breaks that are blunt-ended or have a one base 3' overhang (cells containing nicked, gapped, 3'-recessed, 3'-overhanging ends longer than one base and single-stranded ends are not detected). The high analytic specificity of the ApopTag® ISOL Kit minimizes background due to non-specific labeling of DNA. The specificity can be exploited to more readily identify apoptosis in systems presenting cells with both apoptosis and DNA damage or apoptosis and necrosis. Results are visualized using brightfield microscopy.
Key Applications:
- Immunohistochemistry
- Immunohistochemistry (Paraffin)
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Brand Family:
Chemicon
Detection Methods:
Chromogenic
Promotional Text:
Take 20% off your ApopTag Kit!
Contact Customer Service and mention code ZBIOS516
Contact Customer Service and mention code ZBIOS516
Protein/Isoform Description:
One of the terminal and unmistakable steps in apoptosis is endonucleolytic degradation of cellular DNA. Detection of degraded DNA fragments by Terminal Transferase nick-end-labeling (TUNEL) is a commonly-used method for quantitation of apoptosis.
Product Name:
ApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Kit