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Ordering Information
- : AB15648
- : 100 µg
- : 1 mg/mL
Product Images
Musashi Western blot on mouse liver lysate.
Anti-Musashi
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| M | WB | Rabbit | Affinity Purified | Polyclonal Antibody |
Description:
Anti-Musashi
Trade Name:
Chemicon (Millipore)
Specificity:
Musashi. By Western blot the antibody recognizes a band at ~35 kDa on mouse liver lysate.
Molecular Weight:
35 kDa
Immunogen:
Recombinant Musashi.
Species Reactivity:
Mouse
Application Notes:
Western blot: 1-5 μg/mL on mouse liver lysate.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Purification Method:
Immunoaffinity purified
Presentation:
Purified immunoglobulin. Liquid in PBS with 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- MSI1
- Musashi-1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.
Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: SwissProt: O43347 # RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
SIZE: 362 amino acids; 39125 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity).
TISSUE SPECIFICITY: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
DOMAIN: SwissProt: O43347 The first RNA recognition motif binds more strongly to RNA compared to the second one (By similarity).
SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
SIZE: 362 amino acids; 39125 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity).
TISSUE SPECIFICITY: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
DOMAIN: SwissProt: O43347 The first RNA recognition motif binds more strongly to RNA compared to the second one (By similarity).
SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
Qty/Pk:
100 µg
Brand Family:
Chemicon
Format:
Affinity Purified
Host:
Rabbit
Product Name:
Anti-Musashi
Concentration:
1 mg/mL
Antibody Type:
Polyclonal Antibody