Ordering Information
- : CYL3012
- : 2 mL
hHCN4-CHO K1 Recombinant Cell Line
Description:
hHCN4-CHO K1 Recombinant Cell Line
Trade Name:
Upstate (Millipore)
Product Overview:
Recombinant CHO-K1 cell line expressing the human HCN4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4).
Format:
2 x 1 ml aliquots containing 1.25 x106cells/ml in 10% DMSO at passage 14.
Format:
2 x 1 ml aliquots containing 1.25 x106cells/ml in 10% DMSO at passage 14.
Application Notes:
CHO-K1 cells stably expressing hHCN4 were analyzed by IonWorks™ HT. Over 88% of cells expressed >300 pA outward current (n=1099) with a mean current amplitude of 1360 pA ± 0.03 (n=971). The HCN4 current was inhibited by standard blockers such as capsazepine (pIC50 = 4.2 ± 0.1; n=3) and ZD-7288 (pIC50 = 4.4 ± 0.2; n=4).
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Species:
Hamster
Cell Type:
CHO
Cell Line Type:
Ion Channel Cell Lines
Packaging:
2 x 1 ml aliquots containing 1.25 x 10(e6) cells/ml
Gene Symbol:
HCN4
Protein or Enzyme Type:
Ion Channels