Human PYY (Total) ELISA
Description:
Human PYY (Total) ELISA
Background Information:
Peptide YY (PYY) is a hormone released by the lower GI tract with circulating levels increasing after meals in direct proportion to the caloric content. It is one of the major physiological signals to reduce appetite and food intake. Other functions of PYY are the inhibition of gastric acid secretion, GI motility and pancreatic enzyme output.
Key Applications:
ELISA
Application Notes:
3 hour assay using 20 µL sample size ~ Room Temperature
Species Reactivity:
Human
Precision, %:
- Serum: Intra-assay: 1.5% - 2.7%, Inter-assay: 6.1% - 6.9 %
- Plasma: Intra-assay: 0.9% to 5.8%, Inter-assay: 3.7% - 16.5 %
Sensitivity:
1.4 pg/mL
Therapeutic Areas:
- Diabetes
- Obesity
- Metabolic Disorders
Standard Curve Range:
10 - 2,000 pg/mL
Accuracy:
- Serum: 83.3 – 88.9%
- Plasma: 95.9 – 102.5%
Specificity:
Human PYY 3-36 100%~Human PYY 1-36 104%~Human [Leu31,Pro34] PYY 138%~Human [Pro34] PYY 158%~Porcine, Canine, Rat, or Mouse PYY Not Detectable
Kit Type:
Endocrine Kits
Gene Symbol:
- PYY
- PYY1
- PYY-I
Detection Methods:
Fluorescent
Linearity of Dilution:
- Serum: 97 - 105%
- Plasma: 94 - 99%
Assay Type:
ELISA Assays